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Smith-Waterman Algorithm — Step-by-step Explanations #bioinformatics #algorithm #dynamicprogramming
Smith-Waterman algorithm is a dynamic programming approach used to solve pairwise local sequence alignment. It involves computing a two-dimensional (2D) matrix using the match, mismatch, and gap penalty scores. Solving the matrix consist of three stages: (1) initialization, (2) matrix filling, and (3) traceback. Temple Ferris Smith and Michael ...
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