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  1. MIT Scientists Strip Cancer of Its Sugar Shield - ScienceDaily

    Dec 23, 2025 · MIT scientists strip cancer of its sugar shield Using new molecules that block an immune checkpoint, researchers from MIT & Stanford showed they could stimulate a strong anti-tumor …

  2. Unlocking NK cells: Novel checkpoint targets revolutionize cancer ...

    Aug 5, 2025 · A comprehensive analysis published in Reserch illuminates how cancer cells hijack immune checkpoints on natural killer (NK) cells to disable the body’s frontline defense system.

  3. The present study was initiated by comparing publicly available transcription profiles of tumor tissues from responsive and resistant ICB-treated patients across various cancer types.

  4. CD300a: An Innate Immune Checkpoint Shaping Tumor Immunity …

    Nov 27, 2025 · Recent studies suggest that tumor cells may hijack CD300a-associated pathways to establish an immunosuppressive microenvironment that facilitates immune evasion, tumor survival, …

  5. How Cancer Tumors Hijack the Body’s Defense System

    May 10, 2024 · Authors note that tumors likely employ a variety of strategies to evade immune detection. But the discovery could lead to a new approach for targeted cancer therapies.

  6. A new immunotherapy approach could work for many types of cancer

    Dec 16, 2025 · Using molecules called AbLecs that block an immune checkpoint, researchers showed they could stimulate a strong anti-tumor immune response. The approach, which could work for …

  7. Frontiers | Targeting immune checkpoints on tumor-associated ...

    May 29, 2023 · Tumor-associated macrophages (TAMs) are the predominant immune cells that infiltrate the tumor microenvironment and express a variety of immune checkpoints that impact immune …

  8. The Role of Immune Checkpoint Inhibitors in Cancer Therapy

    Mar 13, 2025 · Humans have been attempting to combat cancer since the time of the Ancient Egyptians, and recent decades have seen remarkable progress. However, tumor cells have developed …

  9. TIGIT protein inhibition could help immune system target cancer cells

    Dec 23, 2025 · Researchers at the University of Sharjah are exploring a promising approach that could enhance the immune system's ability to fight cancer, potentially paving the way for new treatments.

  10. How Cancer ‘Hijacks’ Your Immune System And What You Can Do …

    Feb 4, 2025 · A new study from the Chiba Cancer Center in Japan has revealed that cancer cells can hijack your immune system’s T-cells, stealing their energy and making them ineffective.