1 University Hospitals Leuven and KU Leuven Belgium, Leuven, Belgium The early biological era was a period of euphoria with the approval of several new drugs with different MOA. With the introduction ...

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Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...

Objective We conducted a systematic review to evaluate associations between influenza vaccination during pregnancy and adverse birth outcomes and maternal non-obstetric serious adverse events (SAEs), ...

Objective The Canadian Congenital Diaphragmatic Hernia (CDH) Collaborative sought to make its existing clinical practice guideline, published in 2018, into a ‘living document’. Design and main outcome ...

Diagnostic errors are associated with patient harm and suboptimal outcomes. Despite national scientific efforts to advance definition, measurement and interventions for diagnostic error, diagnosis in ...

The last 10 years have seen a major shift in management of large vessel ischemic stroke with changes towards ever-expanding use of reperfusion therapies (intravenous thrombolysis and mechanical ...

Background While prior literature has documented the impact of housing quality on health, the long-lasting effects of poor housing conditions in adolescence on adult health remain understudied. This ...

Correspondence to Dr Brian D Earp, Faculty of Philosophy, University of Oxford Uehiro Centre for Practical Ethics, Oxford OX1 1PT, UK; brian.earp{at}philosophy.ox.ac.uk This issue considers the ethics ...

Background Endometriosis is a debilitating gynaecological disorder with an elusive pathogenesis. While gut microbiota dysbiosis has been implicated, the causal role of gut-peritoneum microbial ...

Background Wide-necked intracranial aneurysms present unique challenges for endovascular treatment. The Comaneci device is a novel temporary bridging device designed to assist coil embolization ...

In context: Windows has included a proprietary JavaScript engine since the release of Internet Explorer 3.0 nearly 30 years ago. Technically, JScript is Microsoft's own dialect of the ...