The National Observer connects the dots on business trends from cities around the nation to provide actionable business intelligence. Consumer sentiments are shifting ...

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NC Reality Check reflects the Charlotte Observer’s commitment to holding those in power to account, shining a light on public issues that affect our local readers and illuminating the stories that ...

For the seventh consecutive year, Pennsylvania’s Laurel Highlands region is among the nation’s 10 best destinations for fall foliage. The region finished sixth in the USA Today 10 Best Readers’ Choice ...

From highlights and analysis to scores and can't-miss video replays, get all your NFL updates here. Want to see these headlines in your inbox? Sign up for The Scorecard: Your National Sports ...

Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically uses ...

In our 2022 Voter Guide, find out how to register to vote, how to request a mail-in ballot, where to vote early, and what positions the candidates in Wake, Durham, Orange, Johnston and Chatham ...

PITTSBURGH – Mike McCarthy and Aaron Rodgers have been around each other a long time. So much so that when the Pittsburgh Steelers coach told Rodgers and the rest of the offense it was time to "cut it ...

The city’s budget trouble continues to show itself in many important ways.

There are three candidates running to represent NC’s 4th Congressional District. Read their answers to our questions here. . Part of the McClatchy Media Network ...