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VirtualBox is flexible enough to handle many types of 32-bit and 64-bit configurations. If you need to run a 32-bit version of XP in a 64-bit host, you can do that without any problems.
VirtualBox is a general-purpose full virtualizer for x86 hardware. Targeted at server, desktop and embedded use, it is a professional-quality virtualization solution that is also Open Source Software.
If VirtualBox VM is not opening or starting in Windows 11/10, disable Driver Enforcement or set Paravirtualization Interface to KVM and see.