Background. Integrase strand transfer inhibitors (INSTIs) are crucial for the treatment of human immunodeficiency virus (HIV) type 2 infection, due to limited available therapeutic options. Recently, ...
HIV drug resistance (HIVDR) can emerge with use of antiretroviral (ARV) drugs for HIV treatment and prevention. The increasing prevalence of drug-resistant HIV strains poses a serious threat to the ...
LOS ANGELES (Reuters) - Merck & Co. Inc.'s experimental HIV drug in a new class called integrase inhibitors can control the virus in nearly 80 percent of previously treated patients, when combined ...
October 4, 2006 (San Francisco) — A novel integrase inhibitor, MK-0518, appears to broaden treatment options for patients with human immunodeficiency virus (HIV) who have developed resistance to ...
Researchers from the U.S. National Institutes of Health and collaborators recently conducted a study investigating the mechanisms of HIV-1 resistance to integrase strand transfer inhibitors (INSTIs), ...
A panelist discusses how the new doravirine and islatravir combination offers an alternative to integrase inhibitor-based therapies, particularly useful for patients with integrase inhibitor ...
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