Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...

Individuals who develop antibodies against the GluN1 subunit of NMDA receptors can develop NMDA receptor encephalitis (NMDARE), which can lead to psychosis, cognitive deficits and movement disorders.

We all forget things, and sometimes it would be better if we did not. Normal forgetting occurs more frequently as we age, but more serious, progressive, retrograde forgetting, which can have severe, ...

Using cryo-electron microscopy (cryo-EM), researchers captured unprecedented images of key immune system receptors interacting with messenger proteins, elucidating how the receptors change shape upon ...

Researchers at Tohoku University, in collaboration with researchers from the Indian Institute of Technology (IIT) Kanpur, have discovered the working mechanism of an important class of drug target ...

Antibodies are also referred to as immunoglobulins (Ig). Immunoglobulins are large Y-shape proteins that are primarily created by plasma cells. These generally consist of two identical light chains ...