San Francisco quarterback Mac Jones sustained a knee sprain in the 49ers’ second preseason game on Saturday and won’t be available when the NFL team closes its preseason schedule on Saturday.

The 49ers' starting cornerback hurt his hamstring about four weeks ago and has not been practicing since. This has allowed the team to see Dallis Flowers and Darrell Luter under a microscope and may have improved the depth of the unit. Still, they need a healthy Green and he appears on track for week one.

The 49ers have committed to Brock Purdy with a big extension. But the key to that deal is the guy standing behind him in the backfield.

Bitter rivals clash as the San Francisco 49ers and the Las Vegas Raiders go head-to-head in Week 2 of the NFL preseason today.

San Francisco 49ers head coach Kyle Shanahan believes the locker room vibes are much better compared to last season. Aside from the constant injuries leading up to the looming 53-man roster decision, a lot has changed in San Francisco.

San Francisco 49ers wide receiver Brandon Aiyuk is likely itching to get back on the field after suffering a season-ending injury in Week 7 last season, but he and the team may have broken an NFL rule as he works his way back from a torn ACL and MCL.

The San Francisco 49ers already lean heavily on two seventh-round picks, now they may have another in their starting lineup.

Las Vegas Raiders rookie running back Ashton Jeanty ran over a San Francisco 49ers defender in a highlight-reel moment in his second preseason game.