Normal urinary bladder function requires contraction and relaxation of the detrusor smooth muscle (DSM). The DSM undergoes compensatory hypertrophy in response to partial bladder outlet obstruction ...

Sexual function and lower urinary tract function are most commonly considered in the context of the typical individual organ-specific diseases and complaints. Until recently, the clinical problems of ...

β-Catenin phosphorylation plays important roles in modulating its functions, but the effects of different phosphorylated forms of β-catenin in response to heterocellular interaction are unclear. Here ...

Using whole genome sequencing, researchers identified a single variant in a microRNA gene, MIR145-5p, as the source of multisystemic smooth muscle dysfunction syndrome, which had gone undiagnosed in a ...

Researchers have discovered that a key protein controls how stem cells 'choose' to become either skeletal muscle cells that move limbs, or smooth muscle cells that support blood vessels. The results ...

The film explores the muscular system of the human body, detailing the roles and functions of the three types of muscles: skeletal, smooth, and cardiac. Skeletal muscles, which are voluntary and work ...

Traditionally, doctors and clinicians thought diseases that affect muscles or bones affected those areas specifically. For example, bone diseases only affect bones, or muscle diseases only concerned ...

MALIGNANT smooth-muscle tumors (leiomyosarcomas) of soft-tissue origin are rare tumors, as indicated by the fact that in a review of the recent surgical literature, only one series, comprising 36 ...