The Scientist

Advancing Single-Nucleotide Polymorphism Detection

Single-nucleotide polymorphisms (SNPs) are the most prevalent form of genetic variation in the human genome and are linked to many serious diseases, making them crucial markers in clinical diagnosis.
Nature

A novel AllGlo probe-quantitative PCR method for detecting single nucleotide polymorphism in CYP2C19 to evaluate the antiplatelet activity of clopidogrel

CYP2C19 gene has multiple single nucleotide polymorphism (SNP), which is the major determinant for clopidogrel treatment responses. Therefore, CYP2C19 SNP detection is essential for predicting ...
Nature

A retrospective single center analysis of fetuses with region of homozygosity detected by single nucleotide polymorphism array

We assessed the incidence and clinical significance of the fetal region of homozygosity (ROH) detected using single nucleotide polymorphism (SNP) array by analyzing clinical information and pregnancy ...
ascopubs.org

Single Nucleotide Polymorphism of the Human Kallikrein-2 Gene Highly Correlates With Serum Human Kallikrein-2 Levels and in Combination Enhances Prostate Cancer Detection

Phase II Evaluation of Temozolomide and 13-cis-Retinoic Acid for the Treatment of Recurrent and Progressive Malignant Glioma: A North American Brain Tumor Consortium Study Purpose: We examined the ...