Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.

Christopher J. Fallaize, Peter J. Green, Kanti V. Mardia, Stuart Barber, Bayesian protein sequence and structure alignment, Journal of the Royal Statistical Society.

Phylogenetic tree inference is a critical component of many systematic and evolutionary studies. The majority of these studies are based on the two-step process of multiple sequence alignment followed ...

MUSCLE uses a log expectation score to control progressive alignment of the input amino acid sequences. This avoids the need to explicitly generate multiple alignments, thus drastically reducing the ...

Courtesy of European Bioinformatics Institute KNOWLEDGE GAPS? Sequence alignments offer clues to both the function and evolution of novel genes. But a bewildering array of algorithms and parameters ...

Multiple Sequence Alignment Algorithms Publication Trend The graph below shows the total number of publications each year in Multiple Sequence Alignment Algorithms.