Proteins form the building blocks of life, but when they form unusual clumps inside the brain, they raise an alarm that ...

Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...

The formation of amyloid fibrils and the aggregation of misfolded proteins are central to the pathology of Alzheimer’s disease. At the molecular level, normal proteins adopt aberrant conformations ...

A new large-scale study has mapped the first molecular events that drive the formation of harmful amyloid protein aggregates found in Alzheimer's disease, pointing towards a new potential therapeutic ...

Researchers at the VIB-KU Leuven Center for Microbiology and the VIB-KU Leuven Center for Brain & Disease Research revealed a mechanism involving protein aggregation that allows bacteria to enter a ...

Maryland Governor Hogan Visits Genesis Nursing Home as They Receive Their Covid-19 Vaccination on December 23, 2020. Source - Maryland GovPics. CC SA 2.0. Maryland Governor Hogan Visits Genesis ...

Raghu R. Chivukula, MD, Ph.D., a physician-investigator in the Departments of Medicine & Surgery and the Center for Genomic Medicine at Massachusetts General Hospital and Harvard Medical School, is ...

The pathway leading to the telltale sign of ALS, protein aggregation in the cytoplasm of motor neurons, has been revealed. Researchers from the University of California – San Diego (CA, USA) have ...

Researchers have developed a 'self-driving' microscope that can predict the onset of misfolded protein aggregation - a hallmark of neurodegenerative disease - as well as analyze the biomechanical ...

The new treatment leverages peptide-brush polymers, which act as a shield to prevent proteins from binding to one another. Polymer backbone is shown in yellow. Active peptides are in blue and green.

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington’s, Alzheimer’s and Parkinson’s. But to the human eye, proteins that are ...