The application of optical traps has come to the fore in the last three decades. They provide a powerful, sterile and noninvasive tool for the manipulation of cells, single biological macromolecules, ...
Figure 1: An example of the use of the mmTIRFM in a CoSMoS experiment to study spliceosome assembly. Multiwavelength TIRFM often uses an objective-based setup in which TIR is generated by focusing the ...
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