Coordination of microtubules and the actin cytoskeleton is important in several types of cell movement. mDia1 is a member of the formin-homology family of proteins and an effector of the small GTPase ...

Cytoplasmic streaming is the persistent circulation of the fluid contents of large eukaryotic cells, driven by the action of molecular motors moving along cytoskeletal filaments, entraining fluid.

Plant growth and development are a genetically predetermined series of events but can change dramatically in response to environmental stimuli, involving perpetual pattern formation and reprogramming ...

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential exchange of ...

Huntington's disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...

Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...

Researchers have developed photoresponsive derivatives of the anticancer drug Taxol®, which allow light-based control of cytoskeleton dynamics in neurons. The agents can optically pattern cell ...

Huntington’s disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...