Animal development consists of a cascade of tissue differentiation and shape change. Associated mechanical signals regulate tissue differentiation. Here we demonstrate that endogenous mechanical cues ...

Corals first appeared on earth nearly half a billion years ago during the Cambrian Period of the Paleozoic Era. The ancient Greek philosopher Aristotle categorized corals as zoophyta, or ...

Transcription factors have diverse roles during embryonic development, combinatorially controlling cellular states in a spatially and temporally defined manner. Resolving the dynamic transcriptional ...

In a study of over 50 transcription factors, Tbx6 alone was able to stimulate mesoderm formation in laboratory-grown stem cells, and could cause those stem cells to become cardiovascular or ...