Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including ...

A groundbreaking new book – the first of its kind in Chinese – is now available to empower researchers with the powerful tool of Mendelian randomization. Translated from the esteemed text "Mendelian ...

The instrument variable assumptions imply that all trains leaving the departure station (genetic variant) and arriving at the destination (outcome) must pass through the exposure station. They can ...

Using MR-SPI and AlphaFold3, scientists unravel the molecular underpinnings of Alzheimer’s disease, identifying key protein changes that could reshape future treatments. Study: Deciphering proteins in ...

What is MR: MR uses genetic variants as tools to infer causality between exposures and outcomes, reducing confounding common in observational studies. Why it matters: It offers a way to test causal ...