Single-cell analysis is a ubiquitous laboratory technique that allows researchers to probe the myriad biomolecular states of cells. Single-cell assays can reveal gene and protein expression patterns, ...

Optical diffraction tomography (ODT) has long been recognized for its potential in non-invasive, label-free imaging of live biological cells. However, a major challenge arises when ODT is applied to ...

Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their blueprint—the genetic information. Here, the basic building blocks of proteins, ...

No modern laboratory is complete without at least one basic microscope, an essential tool for biologists in medical research. Transmitted light methods have largely been replaced by fluorescent ...

Single-cell functional analysis enables scientists to examine the unique characteristics of each cell within organs, tissues, and cell cultures. Unlike bulk-cell analysis, single-cell analysis allows ...

Single-cell biology has transformed how we decode cellular heterogeneity, but a new frontier is emerging: understanding what individual cells do, not just what they express. The ability to observe ...