In a recent study published in Nature Communications, researchers evaluate the impact of tumor-derived growth and differentiation factor-15 (GDF-15) on leukocyte function-associated antigen 1 ...
Kidney complications in diabetes often progress silently, putting patients at risk of life-threatening outcomes long before any symptoms appear. Identifying individuals with diabetes who are at risk ...
Immune checkpoint blockade therapy is beneficial and even curative for some cancer patients. However, the majority don’t respond to immune therapy. Across different tumor types, pre-existing T cell ...
A multi-institutional clinical trial led by the University of Navarra, Spain, found that blocking growth differentiation factor 15 (GDF-15) can counteract resistance to anti-PD-1 and anti-PD-L1 ...
MUNICH--(BUSINESS WIRE)--CatalYm today announced that the first results from its ongoing Phase 2a trial “GDFATHER-2” (GDF-15 Antibody-mediaTed Human Effector Cell Relocation Phase 2) will be featured ...
Levels of growth differentiation factor-15 (GDF-15), a biomarker of oxidative stress and inflammation, are significantly associated with short-term adverse outcomes among adults presenting to the ...
Growth differentiation factor-8 (GDF-8) is found in the human serum, follicular fluid and granulosa cells. Our previous studies have shown that the human cumulus expansion and steroidogenesis can be ...
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