Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have ...
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p38 MAPK drives epigenetic activation of fibrotic genes in lung fibroblasts
A new research paper was published in Volume 18 of Aging-US on March 3, 2026, titled "P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung ...
NUDT21 regulates fibroblast senescence and is significantly decreased in aged and fibrotic lungs, impacting IPF progression. Alternative polyadenylation (APA) and NUDT21 downregulation enhance STAT3 ...
Cancer-associated fibroblasts (CAFs) get a bad rap. The protective, gel-like complex surrounding tumors have been thought to be a no-go for drugs and are known to enforce treatment resistance. But ...
One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...
Regular erections could be important for maintaining erectile function, according to a new study on mice published in Science by researchers at Karolinska Institutet. “We discovered that an increased ...
Cell-based therapies can be developed in various ways, but companies look for methods that are faster and more efficient. At Houston, TX-based FibroBiologics scientists turn fibroblasts into ...
A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results ...
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Wnt signaling in fibroblasts drives gastric cancer metastasis to the liver
Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to ...
More than 10,000 Americans are waiting for a liver transplant. Many more never make the list, because they are too sick to ...
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