Nature

High expression of transgenes mediated by hybrid retroviral vectors in hepatocytes: comparison of promoters from murine retroviruses in vitro and in vivo

To achieve high transgene expression in the liver, we have compared the reporter gene expression among various murine retroviral long terminal repeats (LTRs) or leader sequences in vitro. Transient ...
Nature

Gene Therapy Progress and Prospects – Vectorology: design and production of expression cassettes in AAV vectors

Expressing large cDNA with rAAV cassettes by using the trans-splicing system or the minigene strategy rAAV vectors can efficiently deliver small RNA molecules Alternative to IRES elements, ‘the ...
The Scientist

Show Me The Money: Prokaryotic Expression Vectors And Purification Systems

For most genes, proteins are the athletic embodiment of these professional activities. Our task as agents then, is to find the correct medium for these proteins to "show their stuff". Occasionally, we ...
GEN

Novel Vectors for Baculovirus Expression

Gene Cloning and Protein Expression in Insect Cells Is Faciliatated by New Methodologies Since the pioneering interferon expression studies conducted in the early 1980s, baculovirus-based expression ...
Contract Pharma

Circio, Tcelltech Enter CAR-T Cell Therapy Research Collaboration

Will combine respective technologies to generate in vivo CAR-T and TCR-T cells with enhanced and more durable expression.
News Medical

The Baculovirus Expression Vector System (BEVS)

The Baculovirus Expression Vector System (BEVS) is used to produce recombinant proteins. This is very useful in regards to virology studies and biotechnology applications. Baculovirus on ice ready to ...