Here we introduce a framework for molecular structure optimization using a denoising model on a physics-informed Riemannian manifold (R-DM). Unlike conventional approaches operating in Euclidean space ...

Threads or ropes can easily be used for braiding, knotting, and weaving. In chemistry, however, processing molecular strands in this way is an almost impossible task. This is because molecules are not ...

Molecular chaperones, a class of complex client regulatory systems, play significant roles in the prevention of protein misfolding and abnormal aggregation, the modulation of protein homeostasis, and ...