This is a preview. Log in through your library . Abstract Serum is an environment in which bacterial cells should not exist. The serum complement system provides innate defense against microbial ...

We are studying the role of the complement system in kidneys and brains during health and disease. Traditionally, major complement proteins were shown to be generated by the liver and are functional ...

Opsonic activity for Streptococcus pneumoniae mediated by the alternative and classic complement pathways and concomitant binding of activated C3 to the bacteria were measured in sera from children ...

Nipocalimab might lower the concentration of anti-acetylcholine receptor antibodies in people with generalized myasthenia gravis, a study shows. PHOENIX, Arizona—Nipocalimab might lower the ...

Figure 1: Complement activation is involved in tumor growth. Because the formation of C3 convertase is the point in the complement cascade at which the three known pathways of complement activation ...

Complement activation contributes to platelet destruction in immune thrombocytopenia (ITP). However, there has been very little data describing serum complement levels in ITP patients, and no data ...

A MARKED increase in the incidence of systemic infections due to gram-negative enteric bacilli has been observed in hospitalized patients since the advent of antibiotic therapy. 1,2 Many of these ...

Traumatic brain injury (TBI) is a major cause of disability and a risk factor for early-onset dementia. The injury is characterized by a physical insult followed acutely by complement driven ...

To clarify the association between certain immunologic factors and clinical activity in patients with systemic lupus erythematosus, 96 patients were studied. Those with antibodies to deoxyribonucleic ...