The FDA’s new draft guidance on Bayesian methodology signals a shift toward more flexible, data-driven clinical trial designs, enabling sponsors to use prior data and adaptive approaches to improve ...

Our laboratory is constantly pushing the limits in analytical performance of direct MS techniques to improve disease detection from tissues and challenging clinical samples such as minimally invasive ...

Innovative statistical method helps determine ideal threshold times in restricted mean survival time analyses. The restricted mean survival time (RMST) analysis technique was introduced in health care ...

Pennington Biomedical Research Center hosted the NIDDK Clinical Methods for Nutrition and Obesity Research Course, an intensive four-day training program designed to equip postdoctoral fellows, ...

The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

Statistical methods now being used in adaptive biomarker-driven clinical trials are reviewed. Some previous paradigms for clinical trial design can limit the development of more effective methods on ...

Infectious lower respiratory diseases and diarrheal diseases are top causes of deaths worldwide, accounting for 4.1 million deaths in 2019. The current COVID-19 pandemic is yet another reminder about ...

Decentralized clinical trials involve a combination of participant-centered design with innovative technologies. Decentralized clinical trials can either be fully remote or adopt a hybrid approach ...