DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

Learn how a newly discovered virus disrupts its host’s nucleus in ways that echo how complex cells may have formed billions ...

Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off ...