New drug helps treat pancreatic cancer
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Lung cancer is the most common and deadly form of cancer worldwide. It is increasingly understood to be a complex genetic disease with different mutations that vary according to factors such as smoking and ethnicity.
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A phase 1/2 trial just reported exceptional disease control on pancreatic cancer using daraxonrasib — a targeted drug aimed at the mutation doctors once called untreatable
For more than three decades, oncologists have watched the same story play out with pancreatic cancer. A patient’s tumor is sequenced. A KRAS mutation is found, as it is in roughly 90 percent of pancreatic ductal adenocarcinomas.
Population-based pathogenic variant testing identified breast cancer susceptibility gene carriers who would often be missed by clinical risk models, even when polygenic risk scores were added. In the WISDOM Study analysis,
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House Cats May Help Unlock New Cancer Treatments
A newly discovered genetic link between cat and human cancer may have major implications for the disease’s treatment in both felines and humans. This significant study of nearly 500 cat tumors from around the world is the largest study on feline cancer genetics conducted to date.