Wif1 overexpression accelerated osteogenic differentiation by activating genes related to late-stage osteogenic differentiation and mitophagy processes. Moreover administering Wif1-overexpressing ...

Scientists uncovered how the protein Piezo1 translates physical activity into stronger bones, offering a path to exercise-mimicking therapies. Scientists from the Department of Medicine, School of ...

Osteocytes, the most abundant cells in bone tissue, have long been underestimated in their functional capacity. Traditionally viewed as passive entities, recent research has illuminated their pivotal ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

New Griffith University research investigated how the Nuralyte device, similar in size to an electric toothbrush, enhanced mitochondrial respiration and stimulated gene expression in bone-forming stem ...

A study conducted by researchers at Baylor College of Medicine and collaborating institutions reveals the molecular events leading to osteogenesis imperfecta type V, a form of brittle bone disease ...

Our fat tissue could be used to make our bones regrow, with scientists successfully using adipose cells to repair spinal compression fractures. It could change how breaks are treated and improve bone ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from the Institute of Science Tokyo, Japan. Hypoxic conditions ...