We performed a noninferiority randomized controlled trial in four different centers that evaluated patients with hematologic malignancies requiring HCT who were randomly assigned to either a ...

Acute myeloid leukemia (AML) is cancer that affects the blood and bone marrow. Doctors may recommend blood transfusions as part of AML treatment. The specific transfusion type and associated risks ...

Jeffrey Carson spent more than a decade persuading hospitals that fewer, resource-saving blood transfusions work just as well as more frequent transfusions for most patients. More recently, the ...

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...

Sickle cell disease (SCD) is a group of inherited blood disorders. Affected hemoglobin inside your red blood cells (RBCs) causes them to lose their flexible donut shape and take on a “C” shape. These ...

Blood transfusion before arrival at a hospital reduces mortality from traumatic hemorrhage and shock. Whether transfusion with whole blood is more beneficial than transfusion with blood components is ...